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J Med Drug Rev 2012;2;31-39

Long-term benefit of early multiple sclerosis treatment with interferon beta-1b: lower disease activity, delayed disability progression, improved overall survival

ABSTRACT (Review-Artikel in deutscher Sprache) Multiple sclerosis (MS) often starts in early adulthood und thereafter typically takes a course over several decades. However, clinical studies in MS with usual treatment periods of...[mehr]

Kategorie: Jahrgang 2012

J Med Drug Rev 2012;2;19-30

Inhibition of mTOR with everolimus for the treatment of advanced renal cell carcinoma after failure of anti-VEGF therapy

ABSTRACT (Review-Artikel in deutscher Sprache) Molecularly targeted therapies have widened considerably the spectrum of medically treatment options for the advanced renal cell carcinoma (RCC). Additionally to cytokines, several...[mehr]

Kategorie: Jahrgang 2012

J Med Drug Rev 2012;2;13-18

Apixaban sets benchmarks for thromboprophylaxis in cases of hip and knee replacement

ABSTRACT (Review-Artikel in deutscher Sprache) Major orthopedic surgical procedures such as knee or hip replacement surgeries are associated with a high risk of deep venous thrombosis (DVT) and related complications. Therefore,...[mehr]

Kategorie: Jahrgang 2012

J Med Drug Rev 2012;2;5-12

Rifaximin and Polyethylene Glycol as treatment modalities in hepatic encephalopathy

ABSTRACT (Review in English and German language) Treatment of hepatic encephalopathy (HE) is still a challenge as the efficacy of the former gold-standard lactulose has been questioned. In addition to disturbed ammonia...[mehr]

Kategorie: Jahrgang 2012

J Med Drug Rev 2011;1;45-52

Belatacept A new immunosuppressant after kidney transplantation acts via selective T-cell costimulation inhibition.

ABSTRACT (Review-Artikel in deutscher Sprache) Belatacept is a new treatment option for the prevention of acute organ rejection in patients after kidney transplantation. Its mode of action totally differs from all known...[mehr]

Kategorie: Jahrgang 2011

J Med Drug Rev 2011;1;29-36

Fingolimod The oral alternative to interferon beta, highly efficient and safe in multiple sclerosis

ABSTRACT (Review-Artikel in deutscher Sprache) Fingolimod is a new significant option for oral treatment of multiple sclerosis. Its mode of action totally differs from all known standard therapies. Fingolimod binds to the...[mehr]

Kategorie: Jahrgang 2011

J Med Drug Rev 2011;1;21-28

Indacaterol in COPD: the first ultra-long-acting ß2-agonist

ABSTRACT (Review-Artikel in deutscher Sprache) The standard maintenance therapy of chronic obstructive pulmonary disease (COPD) comprises the anticholinergic tiotropium as well as long-acting ß2-agonists like salmeterol and...[mehr]

Kategorie: Jahrgang 2011

J Med Drug Rev 2011;1;13-20

Dabigatran for prevention of ischemic stroke in atrial fibrillation: Is the era of vitamin K antagonists coming to an end?

ABSTRACT (Review-Artikel in deutscher Sprache) Patients with atrial fibrillation have a high risk for ischemic stroke and systemic embolism and usually receive vitamin K antagonists for antithrombotic therapy. However, effective...[mehr]

Kategorie: Jahrgang 2011

J Med Drug Rev 2011;1;5-12

Rifaximin: high local antibiotic efficacy in the gastrointestinal tract with minimal systemic bioavailability

ABSTRACT (Review-Artikel in deutscher Sprache) Basics: Rifaximin is an antibiotic exerting local activity in the gastrointestinal tract with a broad efficacy spectrum und minimal systemic bioavailability. Rifaximin differs from...[mehr]

Kategorie: Jahrgang 2011

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